Beef
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Important Safety Information
For Baytril 100:
For use by or on the order of a licensed veterinarian. Extra-label use in foodproducing animals is prohibited.Cattle intended for human consumption must not be slaughtered within 28 days from the last treatment. This product is not approved for female dairy cattle 20 months of age or older,including dry dairy cows. Use in these cattle may cause drug residues in milk and/or in calves born to these cows.The effects of enrofloxacin on cattle or swine reproductive performance,pregnancy and lactation have not been determined.
Caution: Not for human use. Keep out of reach of children. For subcutaneous use in beef cattle and non-lactating dairy cattle.
Federal (U.S.A.) law restricts this drug to use by or on the order of a licensed veterinarian. Federal (U.S.A.) law prohibits the extra-label use of this drug in food-producing animals.
For Baytril 100-CA1:
Federal law restricts this drug to use by or on the order of a licensed veterinarian. Extra-label use of this drug in food-producing animals is prohibited. Cattle intended for human consumption must not be slaughtered within 28 days from the last treatment. This product is not approved for use in female dairy cattle 20 months of age or older including dry dairy cows. Use in these cattle may cause drug residues in milk and/or in calves born to these cows. A withdrawal period has not been established for this product in pre-ruminating calves. Do not use in calves to be processed for veal. The effects of enrofloxacin on bull reproductive performance have not been adequately determined.
Caution: Not for human use. Keep out of reach of children. Federal (U.S.A.) law restricts this drug to use by or on the order of a licensed veterinarian. Federal (U.S.A.) law prohibits the extra-label use of this drug in food-producing animals.
For Experior:
Caution: Not approved for use in breeding animals because safety and effectiveness have not been evaluated in these animals. Do not allow horses or other equines access to feed containing Experior. A decrease in dry matter intake may be noticed in some animals.
The label contains complete use information, including cautions and warnings. Always read, understand, and follow the label, and use directions.
For Increxxa:
Federal law restricts this drug to use by or on the order of a licensed veterinarian. Extra-label use of this drug in food-producing animals is prohibited. Cattle intended for human consumption must not be slaughtered within 18 days from the last treatment. This drug is not approved for use in female dairy cattle 20 months of age or older, including dry dairy cows. Use in these cattle may cause drug residues in milk and/or in calves born to these cows.
Caution: Not for human use. Keep out of reach of children. Do not use in animals previously found to be hypersensitive to the drug. Increxxa has a pre-slaughter withdrawal time of 18 days. Do not use in female dairy cattle 20 months of age or older.
For Loncor:
Federal law restricts this drug to use by or on the order of a licensed veterinarian. Animals intended for human consumption must not be slaughtered within 28 days of the last intramuscular treatment or within 38 days of subcutaneous treatment. This product is not approved for use in female dairy cattle 20 months of age or older, including dry dairy cows. Use in these cattle may cause drug residues in milk and/or calves born to these cows. A withdrawal period has not been stablished in pre-ruminating calves. Do not use in calves to be processed for veal.
Caution: Federal law restricts this drug to use by or on the order of a licensed veterinarian.
For Micotil®:
Micotil is indicated for the treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus somni, and for the control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia haemolytica.
Before using this product, it is important to read the entire product insert, including the boxed human warning.
CAUTION: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian.
- Not for human use. Injection of this drug in humans has been associated with fatalities. Keep out of reach of children. Do not use in automatically powered syringes. Exercise extreme caution to avoid accidental self-injection. In case of human injection, consult a physician immediately, and apply ice or cold pack to injection site while avoiding direct contact with the skin. Avoid contact with eyes.
- Always use proper drug handling procedures to avoid accidental self-injection. Consult your veterinarian on the safe handling and use of all injectable products prior to administration.
- For use in cattle or sheep only. Inject subcutaneously. Injection of this antibiotic has been shown to be fatal in swine and non-human primates, and may be fatal in horses and goats.
- Do not use in female dairy cattle 20 months of age or older. Use in lactating dairy cattle or sheep may cause milk residues.
- The following adverse reactions have been reported: in cattle: injection site swelling and inflammation, lameness, collapse, anaphylaxis/anaphylactoid reactions, decreased food, and water consumption, and death.
- Micotil has a pre-slaughter withdrawal time of 42 days.
For Pulmotil®:
CAUTION: Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.
- Cattle intended for human consumption must not be slaughtered within 28 days of the last treatment.
- To assure both food safety, and responsible use, treatment must be initiated within the first 45 days of the production period. The treatment should not occur concurrent with or following administration of an injectable macrolide, or within 3 days following administration of a non-macrolide injectable BRD therapy.
- VFD expiration date must not exceed 45 days from the time of issuance. VFDs shall not be refilled.
- Use only in cattle fed in confinement for slaughter.
- Cattle with severe clinical illness should be evaluated for individual treatment with an alternative non-macrolide therapy.
- Do not use in female dairy cattle 20 months of age or older or in veal calves.
- Safety has not been established for cattle intended for breeding.
- Do not allow horses or other equines access to feeds containing tilmicosin.
- Avoid inhalation, oral exposure, and direct contact with skin or eyes. Keep out of reach of children.
For Rumensin®:
- Consumption by unapproved species or feeding undiluted may be toxic or fatal. Do not feed to veal calves.
For Tylan® Injection:
- Injection of tylosin in equines has been fatal. Discontinue use in cattle 21 days before slaughter.
For Tylan®:
CAUTION: Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian
For all products:
- The labels contain complete use information, including cautions and warnings. Always read, understand, and follow the labels and use directions.
Dosage/Use Levels
Baytril:
Indications
Cattle – Single-Dose Therapy: Baytril 100 is indicated for the treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida, Histophilus somni and Mycoplasma bovis in beef and non-lactating dairy cattle; and for the control of BRD in beef and non-lactating dairy cattle at high risk of developing BRD associated with M. haemolytica, P. multocida, H. somni and M. bovis.
Cattle – Multiple-Day Therapy: Baytril 100 is indicated for the treatment of BRD associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus somni in beef and non-lactating dairy cattle.
Administration
Single-Dose Therapy (BRD Treatment): Administer, by subcutaneous injection, a single dose of 7.5-12.5 mg/kg of body weight (3.4-5.7 mL/100 lbs.).
Multiple-Day Therapy (BRD Treatment): Administer daily, a subcutaneous dose of 2.5-5 mg/kg of body weight (1.1-2.3 mL/100 lbs.).
Treatment should be repeated at 24-hour intervals for three days. Additional treatments may be given on days 4 and 5 to animals that have shown clinical improvement but not total recovery.
Baytril 100 provides flexible subcutaneous injection dosages and durations of therapy.
Do not use in female dairy cattle 20 months of age or older or in calves to be processed for veal.
Talk with your veterinarian to learn more.
Baytril 100-CA1:
Indications
Baytril 100-CA1 is indicated for the treatment of clinical anaplasmosis associated with Anaplasma marginale in replacement dairy heifers under 20 months of age and all classes of beef cattle, except beef calves less than 2 months of age and beef bulls of any age intended for breeding (any age).
Administration
Single-dose Baytril 100-CA1 is administered by subcutaneous injection at a dose of 12.5 mg/kg of body weight (5.7 mL/100 lbs.). Administered dose volume should not exceed 20 mL per injection site. Use within 30 days of the first puncture and puncture a maximum of 30 times with a needle or four times with a dosage delivery device. Any product remaining beyond these parameters should be discarded. Not for use in any other class of dairy cattle or in veal calves.
Experior:
Label Indication: For reduction of ammonia gas emissions per pound of live weight (LW) and hot carcass weight (HCW) in beef steers and heifers fed in confinement for slaughter during the last 14 to 91 days on feed.
Directions for Use: Feed 1.25 to 4.54 g/ton (1.39 to 5ppm) of complete feed (90% Dray Matter (DM) basis) to provide 13-90 mg lubabegron/head/day continuously to beef steers and heifers fed in confinement for slaughter as the sole ration during the last 14 to 91 days on feed.
Increxxa:
Indications
Beef: Treatment of BRD and control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia haemolytica, Pasteurella multocida, Histophilus somni and Mycoplasma bovis. Treatment of infectious bovine keratoconjunctivitis associated with Moraxella bovis. Treatment of bovine foot rot (interdigital necrobacillosis) associated with Fusobacterium necrophorum and Porphyromonas levii.
Suckling calves, dairy calves and veal calves: Treatment of BRD associated with Mannheimia haemolytica, Pasteurella multocida, Haemophilus somni and Mycoplasma bovis.
Administration
In cattle, inject subcutaneously as a single dose in the neck at a dosage of 2.5 mg/kg (1.1 mL/100 lb) body weight. Do not inject more than 10 mL per injection site.
Loncor:
Indications
Loncor 300 is indicated for treatment of BRD associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus somni, and for the treatment of bovine interdigital phlegmon (foot rot, acute interdigital necrobacillosis, infectious pododermatitis) associated with Fusobacterium necrophorum and Bacteroides melaninogenicus. Also, it is indicated for the control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus somni.
Administration
For treatment of BRD and foot rot:
Single subcutaneous injection to cattle at a dose rate of 40 mg/kg body weight (6 mL/100 lbs.).
Intramuscular injection at a dose rate of 20 mg/kg body weight (3 mL/100 lbs.). A second dose should be administered 48 hours later.
For control of BRD in high-risk cattle:
Single subcutaneous injection to cattle at a dose rate of 40 mg/kg body weight (6 mL/100 lbs.).
Do not administer more than 10 mL at each site. The injection should be given only in the neck.
Not for use in female dairy cattle 20 months of age or older or in calves to be processed for veal.
Rumensin: Growing beef steers and heifers fed in confinement for slaughter:
For improved feed efficiency: Feed 5 to 40 g/ton of monensin (90% DM basis) continuously in a complete feed to provide 50 to 480 mg/hd/d.
For the prevention and control of coccidiosis due to Eimeria bovis and Eimeria zuernii: Feed 10 to 40 g/ton (90% DM basis) continuously to provide 0.14 to 0.42 mg/lb of body weight/d, depending upon severity of challenge, up to a maximum of 480 mg/hd/d.
Rumensin: Growing beef steers and heifers on pasture (stocker, feeder, and slaughter) or in dry lot:
For increased rate of weight gain: Feed 50 to 200 mg/hd/d in at least 1.0 lb of Type C Medicated Feed. Or, after the 5th day, feed 400 mg/hd/d every other day in at least 2.0 lbs of Type C Medicated Feed. The Type C medicated feed must contain 15 to 400 g/ton of monensin (90% DM basis).
For the prevention and control of coccidiosis due to Eimeria bovis and Eimeria zuernii: Feed at a rate to provide 0.14 to 0.42 mg/lb of body weight/d, depending upon severity of challenge, up to a maximum of 200 mg/hd/d. The Type C Medicated Feed must contain 15 to 400 g/ton (90% DM basis).
Type C free-choice medicated feeds: All Type C free-choice medicated feeds containing Rumensin must be manufactured according to FDA-approved formula/specification. When using a formula/specification published in the Code of Federal Regulations (CFR), a Medicated Feed Mill license is not required. Use of Rumensin in a proprietary formula/specification not published in the CFR requires prior FDA approval and a Medicated Feed Mill license.
Rumensin: Beef Cows
For improved feed efficiency when receiving supplemental feed: Feed continuously at a rate of 50 to 200 mg/hd/d. Cows on pasture or in drylot must receive a minimum of 1.0 lb of Type C Medicated Feed/hd/d. Do not self feed.
For the prevention and control of coccidiosis due to Eimeria bovis and Eimeria zuernii: Feed at a rate of 0.14 to 0.42 mg/lb of body weight/d, depending upon severity of challenge, up to a maximum of 200 mg/hd/d.
Rumensin: Calves (excluding veal calves)
For the prevention and control of coccidiosis due to Eimeria bovis and Eimeria zuernii: Feed at a rate of 0.14 to 1.00 mg/lb of body weight/d, depending upon severity of challenge, up to a maximum of 200 mg/hd/d. The Type C Medicated Feed must contain 10 to 200 g/ton (90% DM basis).
Tylan®
For the reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes: Feed continuously as the sole ration at 8 to 10 g/ton of tylosin (90% DM basis) to provide 60 to 90 mg/hd/d.
Optaflexx®: Complete feed
For increased rate of weight gain, and improved feed efficiency: Feed 8.2 to 24.6 g/ton of ractopamine hydrochloride (90% DM basis) continuously in a complete feed to provide 70 to 430 mg/hd/d for the last 28 to 42 days on feed.
For increased rate of weight gain, improved feed efficiency, and increased carcass leanness: Feed 9.8 to 24.6 g/ton of ractopamine hydrochloride (90% DM basis) continuously in a complete feed to provide 90 to 430 mg/hd/d for the last 28 to 42 days on feed.
Optaflexx®: Top dress
For increased rate of weight gain, and improved feed efficiency: Feed 70 to 400 mg/hd/d of ractopamine hydrochloride (90% DM basis) continuously in a minimum of 1.0 lb/hd/d top dress Type C medicated feed (maximum 800 g/ton ractopamine hydrochloride) for the last 28 to 42 days on feed.
Pulmotil®
For the control of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni in groups of beef and non-lactating dairy cattle, where active BRD has been diagnosed in at least 10% of the animals in the group: Feed continuously for a single, 14-day period at 568 to 757 g/ton of tilmicosin (100% DM basis) in a Type C medicated feed as the sole ration to provide 12.5 mg/kg of body weight/day.
Implants
Administer one dose in the ear subcutaneously according to label directions.
Tylan® Injection
For use in the treatment of bovine respiratory complex (shipping fever, pneumonia) usually associated with Pasteurella multocida and Arcanobacterium pyogenes; foot rot (necrotic pododermatitis) and calf diphtheria caused by Fusobacterium necrophorum and metritis caused by Arcanobacterium pyogenes: Inject intramuscularly 8 mg/lb one time daily. Treatment should be continued 24 hours following remission of disease signs, not to exceed 5 days. Do not inject more than 10 mL per site.
Vaccine Precautions:
Do not use Titanium® BRSV 3, Titanium® 3 LP, Titanium® 3, Titanium® IBR LP, and Titanium® IBR in pregnant cows or in calves nursing pregnant cows. Abortions may result.
1. Garcia, D., Garrison, M., Swingle, R. April 2005. “The Value of Group-Based Cattle Sorting.”
Benchmark, Full Value Beef, Component, Compudose, Encore, Experior, Increxxa, Loncor,HeifermaX, MasterGuard, Micotil, Nuplura, Optaflexx, Pulmotil, Rumensin, ScourBos, Tylan, Titanium, and ViraShield are trademarks of Elanco or its affiliates.
Other product names are trademarks of their respective owners.